IL16 蛋白
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- 抗原 See all IL16 蛋白
- IL16 (Interleukin 16 (IL16))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Functional Studies (Func)
- 原理
- Recombinant Human Interleukin-16/IL-16
- 序列
- MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
- 产品特性
- Recombinant Human Interleukin-16/IL-16 produced in E. coli is a single non-glycosylated polypeptide chain containing 130 amino acids with a molecular mass of 13.4 kDa.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IL16 蛋白
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Interleukin 16 (IL16) (AA 1203-1332) (Active) protein (His tag)
IL16 宿主: 人 宿主: 大肠杆菌（E. Coli） > 97 % CC, AcA Active
Interleukin 16 (IL16) (AA 1212-1332) protein (His-IF2DI Tag)IL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 16 (IL16) (AA 1-454) protein (GST tag)IL16 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 说明
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Biological activity: Specific Activity is greater than 1.0 x 104 IU/mg as determined by the ability of Recombinant IL-16 to chemoattract human CD4+ T lymphocytes using a concentration range of 10.0-100.0 ng/ml
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- IL16 (Interleukin 16 (IL16))
- 别名
- il-16 (IL16 产品)
- 别名
- IL16 Protein, LCF Protein, NIL16 Protein, PRIL16 Protein, prIL-16 Protein, mKIAA4048 Protein, IL-16 Protein, interleukin 16 Protein, IL16 Protein, Il16 Protein
- 背景
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Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.ReferencesFeng M, et al. C16 peptide shown to prevent leukocyte infiltration and alleviate detrimental inflammation in acute allergic encephalomyelitis model.PMID: 23352465http://www.ncbi.nlm.nih.gov/pubmed/23352465
Alternative Names: Pro-Interleukin-16, Interleukin-16, IL-16, Lymphocyte Chemoattractant Factor, LCF, IL16 - 分子量
- 13.4 kDa
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