AKR1C2 Protein (AA 1-323)
Quick Overview for AKR1C2 Protein (AA 1-323) (ABIN1096530)
抗原
See all AKR1C2 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-323
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原理
- Recombinant Human Aldo-Keto Reductase 1C2/AKR1C2
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序列
- MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEAVKL AIEAGFHHID SAHVYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA MEKCKDAGLA KSIGVSNFNH RLLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY
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产品特性
- Recombinant Human Aldo-Keto Reductase Family 1 Member C2/AKR1C2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Tyr323) of Human AKR1C2.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (His tag)
custom-made AKR1C2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-256) protein (His tag)AKR1C2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 224-323) protein (GST tag)AKR1C2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (GST tag)AKR1C2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323), (full length) protein (His-SUMO Tag)AKR1C2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) protein (Myc-DYKDDDDK Tag)AKR1C2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- -80 °C
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储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
有效期
- 6 months
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- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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别名
- DDH2
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背景
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Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-alpha/5-beta-Steroid Reductases to convert Steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-alpha-Dihydrotestosterone (5-alpha-DHT) to 5-alpha-Androstane-3-alpha, 17-beta-diol (3-alpha-diol).
Alternative Names: Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase, Type III 3-Al -
分子量
- 36.74 kDa
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UniProt
- P52895
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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