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CNTF Protein (AA 1-200)

This Recombinant CNTF protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1096416
发货至: 中国

Quick Overview for CNTF Protein (AA 1-200) (ABIN1096416)

抗原

See all CNTF 蛋白
CNTF (Ciliary Neurotrophic Factor (CNTF))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-200

    原理

    Recombinant Human Ciliary Neurotrophic Factor/CNTF

    序列

    AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTESYVKH QGLNKNINLD SADGMPVAST DQWSELTEAE RLQENLQAYR TFHVLLARLL EDQQVHFTPT EGDFHQAIHT LLLQVAAFAY QIEELMILLE YKIPRNEADG MPINVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM

    产品特性

    Recombinant Human Ciliary Neurotrophic Factor/CNTF is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Met200) of Human CNTF.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM Cysteine, pH 7.4.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    CNTF (Ciliary Neurotrophic Factor (CNTF))

    别名

    cntf

    背景

    Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
    Alternative Names: Ciliary Neurotrophic Factor, CNTF

    分子量

    22.93 kDa

    UniProt

    P26441

    途径

    JAK/STAT Signaling
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