BMP2 Protein (AA 283-396)
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- 抗原 See all BMP2 蛋白
- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 283-396
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Functional Studies (Func)
- 原理
- Recombinant Human Bone Morphogenetic Protein 2/BMP-2
- 序列
- MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
- 产品特性
- Recombinant Human Bone Morphogenetic Protein 2/BMP-2 is produced by our E. coli expression system. The target protein is expressed with sequence (Gln283-Arg396) of Human BMP-2.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BMP2 蛋白
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- 说明
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Biological activity: Recombinant BMP-2 is fully biologically active when compared to standards.ED50 is less than 50 ng/ml as determined by the cytolysis of MC3T3-E1 cells.Specific Activity of 2.0 x 104 IU/mg
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in 50 mM Acetic acid.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 50 mM HAc .
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
- 别名
- bmp-2 (BMP2 产品)
- 背景
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Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.ReferencesWu T, et al. miR-30 family members negatively regulate osteoblast differentiation.PMID: 22253433, PMCID: PMC3293535http://www.ncbi.nlm.nih.gov/pubmed/22253433
Alternative Names: Bone Morphogenetic Protein 2, BMP-2, Bone Morphogenetic Protein 2A, BMP-2A, BMP2, BMP2A - 分子量
- 13.3 kDa
- UniProt
- P12643
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
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