BMP2 Protein (AA 283-396)
Quick Overview for BMP2 Protein (AA 283-396) (ABIN1096139)
抗原
See all BMP2 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 283-396
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原理
- Recombinant Human Bone Morphogenetic Protein 2/BMP-2
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序列
- MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
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产品特性
- Recombinant Human Bone Morphogenetic Protein 2/BMP-2 is produced by our E. coli expression system. The target protein is expressed with sequence (Gln283-Arg396) of Human BMP-2.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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说明
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Biological activity: Recombinant BMP-2 is fully biologically active when compared to standards.ED50 is less than 50 ng/ml as determined by the cytolysis of MC3T3-E1 cells.Specific Activity of 2.0 x 104 IU/mg
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in 50 mM Acetic acid.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 50 mM HAc .
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
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别名
- bmp-2
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背景
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Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.ReferencesWu T, et al. miR-30 family members negatively regulate osteoblast differentiation.PMID: 22253433, PMCID: PMC3293535http://www.ncbi.nlm.nih.gov/pubmed/22253433
Alternative Names: Bone Morphogenetic Protein 2, BMP-2, Bone Morphogenetic Protein 2A, BMP-2A, BMP2, BMP2A -
分子量
- 13.3 kDa
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UniProt
- P12643
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
抗原
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