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DEFB4A Protein (AA 24-64)

This Recombinant DEFB4A protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1096116
发货至: 中国

Quick Overview for DEFB4A Protein (AA 24-64) (ABIN1096116)

抗原

See all DEFB4A (DEFB4) 蛋白
DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

蛋白类型

Recombinant

宿主

  • 4
  • 1
  • 1

资源

  • 4
  • 2
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 24-64

    原理

    Recombinant Human β-Defensin 4A

    序列

    GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P

    产品特性

    Recombinant Human beta-Defensin 4A is produced with our E. coli expression system. The target protein is expressed with sequence (Gly24-Pro64) of Human beta-Defensin 4A.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

    别名

    beta-Defensin-4A

    背景

    Beta-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 beta-Defensins, which are distinguished from alpha-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. beta-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
    Alternative Names: Beta-Defensin 4A, Beta-Defensin 2, BD-2, hBD-2, Defensin, Beta 2, Skin-Antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B

    分子量

    4.33 kDa

    UniProt

    O15263
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