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beta Defensin 1 Protein (AA 22-68)

This Recombinant beta Defensin 1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1096113
发货至: 中国

Quick Overview for beta Defensin 1 Protein (AA 22-68) (ABIN1096113)

抗原

See all beta Defensin 1 (DEFB1) 蛋白
beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 22-68

    原理

    Recombinant Human β-Defensin 1/DEFB1

    序列

    GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK

    产品特性

    Recombinant Human beta-Defensin 1/DEFB1 is produced with our E. coli expression system. The target protein is expressed with sequence (Gly22-Lys68) of Human DEFB1.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

    别名

    beta-defensin-1

    背景

    Beta-Defensin 1 (DEFB1) is a member of the beta-defensin family, which is highly expressed by epithelial cells. beta-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta-defensin 1 is associated with induction profiles in gingival keratinocytes.
    Alternative Names: Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1

    分子量

    5.07 kDa

    UniProt

    P60022
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