ADAR Protein (AA 1-176) (His-SUMO Tag)
(2 references)Quick Overview for ADAR Protein (AA 1-176) (His-SUMO Tag) (ABIN1095574)
抗原
See all ADAR 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-176
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标记
- This ADAR protein is labelled with His-SUMO Tag.
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序列
- MNPRQGYSLS GYYTHPFQGY EHRQLRYQQP GPGSSPSSFL LKQIEFLKGQ LPEAPVIGKQ TPSLPPSLPG LRPRFPVLLA SSTRGRQVDI RGVPRGVHLG SQGLQRGFQH PSPRGRSLPQ RGVDCLSSHF QELSIYQDQE QRILKFLEEL GEGKATTAHD LSGKLGTPKK EINRVL
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产品特性
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-1178) protein (His tag)
custom-made ADAR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-1226) protein (His tag)custom-made ADAR 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Adenosine Deaminase, RNA-Specific (ADAR) (AA 2-110) protein (GST tag)ADAR 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Adenosine Deaminase, RNA-Specific (ADAR) (AA 1-176), (partial) protein (GST tag)ADAR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Adenosine Deaminase, RNA-Specific (ADAR) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)ADAR 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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说明
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The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2-2 mg/mL
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缓冲液
- Tris-based buffer, 50 % glycerol
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注意事项
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
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储存条件
- -20 °C
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储存方法
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
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: "Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase." in: Molecular and cellular biology, Vol. 15, Issue 10, pp. 5376-88, (1995) (PubMed).
: "Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 24, pp. 11457-61, (1994) (PubMed).
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: "Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase." in: Molecular and cellular biology, Vol. 15, Issue 10, pp. 5376-88, (1995) (PubMed).
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- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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别名
- Double-stranded RNA-specific adenosine deaminase protein
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背景
- Converts multiple adenosines to inosines and creates I/U mismatched base pairs in double-helical RNA substrates without apparent sequence specificity. Has been found to modify more frequently adenosines in AU-rich regions, probably due to the relative ease of melting A/U base pairs as compared to G/C pairs. Functions to modify viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses. Edits the messenger RNAs for glutamate receptor (GLUR) subunits by site-selective adenosine deamination. Produces low-level editing at the GLUR-B Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. Binds to ILF3/NF90 and up-regulates ILF3-mediated gene expression.
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分子量
- 47 kD
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UniProt
- P55265
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途径
- Protein targeting to Nucleus
抗原
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