ADIPOQ Protein (AA 18-247, full length) (His tag)
(2 references)Quick Overview for ADIPOQ Protein (AA 18-247, full length) (His tag) (ABIN1046479)
抗原
See all ADIPOQ 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 18-247, full length
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标记
- This ADIPOQ protein is labelled with His tag.
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序列
- EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYVYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN
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产品特性
- Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
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Adiponectin (ADIPOQ) (Active) protein
ADIPOQ 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Adiponectin (ADIPOQ) (AA 19-244) protein (His tag)ADIPOQ 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 18-247) protein (His tag)ADIPOQ 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 19-244) protein (Fc Tag)ADIPOQ 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 18-247) protein (Fc Tag)ADIPOQ 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Adiponectin (ADIPOQ) protein (His tag)ADIPOQ 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Adiponectin (ADIPOQ) (AA 111-247) protein (His tag)ADIPOQ 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Adiponectin (ADIPOQ) (AA 111-210) protein (GST tag)ADIPOQ 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Adiponectin (ADIPOQ) (AA 111-247) proteinADIPOQ 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Adiponectin (ADIPOQ) proteinADIPOQ 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
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说明
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0, 200 mM Imidazole
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储存条件
- -20 °C
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: "Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity." in: The Journal of biological chemistry, Vol. 277, Issue 22, pp. 19521-9, (2002) (PubMed).
: "The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. ..." in: Nature medicine, Vol. 7, Issue 8, pp. 941-6, (2001) (PubMed).
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: "Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity." in: The Journal of biological chemistry, Vol. 277, Issue 22, pp. 19521-9, (2002) (PubMed).
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- Adiponectin
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背景
- Synonyms: 30 kDa adipocyte complement-related protein,Adipocyte complement-related 30 kDa protein,ACRP30,Adipocyte, C1q and collagen domain-containing protein,Adipocyte-specific protein AdipoQ
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分子量
- 29 kD
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UniProt
- Q60994
抗原
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