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Human Polyclonal SWAP70 Primary Antibody for ELISA, WB - ABIN544049
Hilpelä, Oberbanscheidt, Hahne, Hund, Kalhammer, Small, Bähler: SWAP-70 identifies a transitional subset of actin filaments in motile cells. in Molecular biology of the cell 2003
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Human Polyclonal SWAP70 Primary Antibody for RV Prod, WB - ABIN4357136
Kegel, Jaegle, Driegen, Aunin, Leslie, Fukata, Watanabe, Fukata, Meijer: Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination. in Development (Cambridge, England) 2014
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Human Monoclonal SWAP70 Primary Antibody for ELISA, WB - ABIN524958
Chang, Shu, Lai, Ching-Yu, Chuu, Morishita, Ichikawa, Jessberger, Fukui: SWAP-70 contributes to spontaneous transformation of mouse embryo fibroblasts. in Experimental cell research 2015
Cow (Bovine) Polyclonal SWAP70 Primary Antibody for WB - ABIN2782542
Rosati, Krebs, Liu: Emissions from cooking microwave popcorn. in Critical reviews in food science and nutrition 2007
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Human Polyclonal SWAP70 Primary Antibody for ELISA, WB - ABIN546829
Pearce, Angeli, Randolph, Junt, von Andrian, Schnittler, Jessberger: Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs. in Nature immunology 2006
Human Polyclonal SWAP70 Primary Antibody for ICC, IF - ABIN4357135
Baranov, Revelo, Dingjan, Maraspini, Ter Beest, Honigmann, van den Bogaart: SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis. in Cell reports 2016
Results show that SWAP70 regulates lamellipodia. SWAP70 undergoes conformational regulation at the leading edge of migratory glioma cell line.
Expression of switch-associated protein 70 is associated with lymphocyte activation and reduced disability in multiple sclerosis.
These data show a key role for SWAP70 as a scaffold for tethering the peripheral actin cage to phagosomes.
SWAP70 appears to act as a molecular intermediate between vGPCR and endothelial activation.
SWAP70 may be a target of miR-145, and it might have a potential oncogenic function.
Detection of SWAP70 antibodies during the attack period might suggest that SWAP70 is involved in Multiple Sclerosis relapse pathogenesis
The unwinding of the C-terminal alpha-helix could regulate the functions of SWAP-70 at the plasma membrane surface.
findings suggest that regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure
protein that functions as the only B cell-specific component of an isotype switch recombination
Overexpression of SWAP-70 altered the actin organization and lamellipodial morphology
the binding activity of SWAP-70 to non-muscle F-actin is required for membrane ruffling.
surface expression of SWAP-70 on HIV-1 infected cells as well as PBMCs; SWAP-70 may serve as a marker for T cell differentiation as well as for HIV-1 infection
SWAP-70 may be involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates.
Studies indicate that the autoimmune phenotype in DEF6 and SWAP-70 knock-out (DKO) mice is characterized by the accumulation of B cell subset that expresses high levels of CD11c and T-bet (ABCs).
findings show characteristic changes in the lipidome of CD11c+ immune cells upon their activation, and reveal an important role of SWAP-70 in the selective generation and localization of ceramides
DEF6 and SWAP70 are SWEF proteins with important contributors to hematopoietic stem and precursor cells biology
SWAP-70 is not a typical oncogene, but is required for spontaneous transformation of mouse embryo fibroblasts.
These findings reveal an important role of SWAP-70 in the dynamic spatiotemporal regulation of F-actin networks.
Cells expressing the mutant SWAP-70 exhibited faster growth than the parental or wild-type SWAP-70-expressing cells underscoring its role in neoplastic transformation.
SWAP-70 is not required for podosome formation and F-actin turnover in dendritic cells.
SWAP-70 deficiency reveals two pathways that contribute to spontaneous maturation of DCs.
SWAP-70 controls IgE production through regulation of the antagonistic STAT6 and BCL6 occupancy of the germline IgE promoter
A novel function of the F-actin binding and regulatory protein SWAP-70 in osteoclast biology, is reported.
regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure.
SWAP-70 regulates erythropoiesis by controlling alpha4 integrin.
in a dose-dependent manner, SWAP-70 controls IRF-4 protein expression and thereby regulates the initiation of plasma cell differentiation
SWAP-70-374 can activate some signaling pathways, including the ERK1/2 pathway, to transform MEFs
These data demonstrate SWAP-70 as a novel regulator of S1P signaling necessary for dendritic cell motility and endocytosis.
regulator of the cell adhesion and B-cell differentiation
In mast cells SWAP-70 plays a role both in establishing the initial competence to degranulate and to develop into mature mast cells.
SWAP-70 is an important regulator of specific effector pathways in c-kit signaling, including mast cell activation, migration, and cell adhesion
These data identify SWAP-70 as a transient component of early macropinosomes.
SWAP-70 deficiency uncouples germinal center formation from T-dependent antibody and long-lived plasma cell production and causes extrafollicular generation of high-affinity plasma cells, but does not adequately support the memory response.
data indicate that SWAP-70 may be involved in regulating motility of trophoblast cells during embryonic implantation and placentation.
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
switch-associated protein 70
, SWAP complex protein, 70 kDa
, SWA-70 protein
, SWAP complex protein
, SWAP-70 protein
, SWAP switching B-cell complex 70kDa subunit
, switch-associated protein 70-like
, SWAP switching B-cell complex subunit 70
, SWAP switching B-cell complex 70a subunit 70a
, SWAP switching B-cell complex subunit 70a
, uncharacterized protein LOC393645