This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
Jiang, Shi, Wei, Li, Yang, Wang, Liu, Chen, Tu, Li, Li: "Serum amyloid A, protein Z, and C4b-binding protein β chain as new potential biomarkers for pulmonary tuberculosis." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173304, (2017) (PubMed).
Liu, Li, Luo, Dai, Zhao, Li, Jie, Wang, Huang, Wei: "Low protein Z plasma level is a risk factor for acute myocardial infarction in coronary atherosclerosis disease patients." in: Thrombosis research, Vol. 148, pp. 25-31, (2016) (PubMed).
Aliases for PROZ ELISA试剂盒
protein Z, vitamin K dependent plasma glycoprotein (PROZ) ELISA试剂盒 protein Z, vitamin K-dependent plasma glycoprotein (Proz) ELISA试剂盒 protein Z, vitamin K-dependent plasma glycoprotein b (prozb) ELISA试剂盒 hemoglobin Z, beta-like embryonic chain (Hbb-bh1) ELISA试剂盒 1300015B06Rik ELISA试剂盒 betaH1 ELISA试剂盒 PZ ELISA试剂盒