This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010].
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Xu, Xing, Chen, Chao, Lin, Fan, Yu, Strack, Jeffrey, Shi: "Structure of the protein phosphatase 2A holoenzyme." in: Cell, Vol. 127, Issue 6, pp. 1239-51, (2006) (PubMed).
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