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PPP1R8 产品

(Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

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This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008].

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Featured PPP1R8 Categories

PPP1R8 抗体

High quality antibodies with extensive validation data.

PPP1R8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPP1R8 抗体

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Cat. No. ABIN7161805
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Cat. No. ABIN519111
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Recommended PPP1R8 蛋白

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Cat. No. ABIN7124669
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Cat. No. ABIN1316004
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Cat. No. ABIN1316003
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Latest Publications for our PPP1R8 Products

Nuytten, Beke, Van Eynde, Ceulemans, Beullens, Van Hummelen, Fuks, Bollen: "The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing." in: Oncogene, Vol. 27, Issue 10, pp. 1449-60, (2008) (PubMed).

Beullens, Bollen: "The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly." in: The Journal of biological chemistry, Vol. 277, Issue 22, pp. 19855-60, (2002) (PubMed).

Synonyms and alternative names related to PPP1R8

protein phosphatase 1 regulatory subunit 8 (PPP1R8), protein phosphatase 1, regulatory subunit 8 (Ppp1r8), protein phosphatase 1, regulatory (inhibitor) subunit 8 (Ppp1r8), protein phosphatase 1, regulatory subunit 8b (ppp1r8b), protein phosphatase 1 regulatory subunit 8 L homeolog (ppp1r8.L), protein phosphatase 1 regulatory subunit 8 (Ppp1r8), protein phosphatase 1, regulatory subunit 8a (ppp1r8a), protein phosphatase 1 regulatory subunit 8 S homeolog (ppp1r8.S), 6330548N22Rik, ARD-1, ard-1, ARD1, ard1, AU044684, NIPP-1, nipp-1, NIPP1, nipp1, PPP1R8, ppp1r8, PRO2047, si:ch211-206a7.1

Protein level used designations for PPP1R8

  • RNase E
  • activator of RNA decay
  • nuclear inhibitor of protein phosphatase 1
  • nuclear inhibitor of protein phosphatase-1 alpha
  • nuclear subunit of PP-1
  • protein phosphatase 1 regulatory subunit 8
  • protein phosphatase 1, regulatory (inhibitor) subunit 8
  • NIPP-1
  • protein phosphatase 1 regulatory inhibitor subunit 8
  • protein phosphatase 1, regulatory inhibitor subunit 8
  • uncharacterized protein LOC799896
  • protein phosphatase 1, regulatory (inhibitor) subunit 8a
  • protein phosphatase 1, regulatory subunit 8a
  • protein phosphatase 1 regulatory subunit 8 S homeolog
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