我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PPP1R12A 抗体

(Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009].

recommended

PPP1R12A 抗体 (C-Term) (ABIN6391349)

Verified PPP1R12A 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

显示详细信息

recommended

PPP1R12A 抗体 (AA 1-200) (ABIN6146059)

PPP1R12A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

显示详细信息

recommended

PPP1R12A 抗体 (N-Term) (ABIN3043902)

PPP1R12A 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

显示详细信息

PPP1R12A 抗体 by Grade

Find PPP1R12A 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 适用

Find PPP1R12A 抗体 for a variety of species such as anti-Mouse PPP1R12A, anti-Human PPP1R12A, anti-Rat PPP1R12A. The species listed below are among those available. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 应用范围

Find PPP1R12A 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 抗体来源

Find PPP1R12A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 抗原表位

Find PPP1R12A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PPP1R12A 抗体. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 克隆

Find PPP1R12A 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PPP1R12A 抗体 by 标记

Find PPP1R12A 抗体 with a specific conjugate such as Biotin, AbBy Fluor® 350, AbBy Fluor® 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PPP1R12A 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-PPP1R12A 抗体 (C-Term)

Reactivity Human

Application IHC, ELISA, IF, FACS

Validations

Cat. No. ABIN6391349

Quantity 100 μg

Datasheet Datasheet

anti-PPP1R12A 抗体 (AA 1-200)

Reactivity Human

Application WB, IF, IP

Validations

Cat. No. ABIN6146059

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (N-Term)

Reactivity Human, Monkey, Mouse, Rat

Application WB, IHC, IF, FACS, ICC

Validations

Cat. No. ABIN3043902

Quantity 100 μg

Datasheet Datasheet

anti-PPP1R12A 抗体 (C-Term)

Reactivity Human, Mouse, Rat

Application WB, IHC, ELISA

Validations

Cat. No. ABIN6263491

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pThr696)

Reactivity Human, Rat

Application WB, FACS

Validations

Cat. No. ABIN744068

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pThr853)

Reactivity Human

Application WB, IHC, ELISA

Validations

Cat. No. ABIN7182058

Quantity 100 μg

Datasheet Datasheet

anti-PPP1R12A 抗体 (Ser507)

Reactivity Human, Mouse

Application WB

Validations

Cat. No. ABIN6242457

Quantity 200 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pThr853)

Reactivity Human, Mouse, Rat

Application WB, IHC, ELISA

Validations

Cat. No. ABIN3182548

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (AA 710-970)

Reactivity Human

Application WB, IHC

Validations

Cat. No. ABIN6146060

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pSer696)

Reactivity Chicken, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)

Application WB, IHC, IF, IC

Validations

Cat. No. ABIN7303414

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pThr853)

Reactivity Mouse, Rat

Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)

Validations

Cat. No. ABIN744083

Quantity 100 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (AA 824-857)

Reactivity Human, Mouse, Rat

Application WB

Validations

Cat. No. ABIN6242461

Quantity 200 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pSer668)

Reactivity Human

Application WB

Validations

Cat. No. ABIN6241041

Quantity 200 μL

Datasheet Datasheet

anti-PPP1R12A 抗体

Reactivity Human, Mouse, Rat

Application WB, ELISA

Validations

Cat. No. ABIN7237456

Quantity 200 μL

Datasheet Datasheet

anti-PPP1R12A 抗体 (pThr852)

Reactivity Mouse

Application WB

Validations

Cat. No. ABIN6241043

Quantity 200 μL

Datasheet Datasheet

Latest Publications for our PPP1R12A 抗体

Xiaojun, Yan, Hong, Xianghong, Shifeng, Dingjie, Xuemin, Lijuan, Bonan, Zhongqiu, Ruimin, Brann, Fang: "Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica." in: Scientific reports, Vol. 6, pp. 32257, (2018) (PubMed).

Ye, Jing, Li, Wu, Li, Xu: "Icariin promotes proliferation and osteogenic differentiation of rat adipose-derived stem cells by activating the RhoA-TAZ signaling pathway." in: Biomedicine & pharmacotherapy, Vol. 88, pp. 384-394, (2017) (PubMed).

Yan, Wang, Jiang, Chen, He, Mang, Shao, Xu: "The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia." in: Neural regeneration research, Vol. 10, Issue 9, pp. 1441-9, (2015) (PubMed).

Lutter, Barger, Nair, Hackstadt: "Chlamydia trachomatis inclusion membrane protein CT228 recruits elements of the myosin phosphatase pathway to regulate release mechanisms." in: Cell reports, Vol. 3, Issue 6, pp. 1921-31, (2013) (PubMed).

Khatri, Joyce, Brozovich, Fisher: "Role of myosin phosphatase isoforms in cGMP-mediated smooth muscle relaxation." in: The Journal of biological chemistry, Vol. 276, Issue 40, pp. 37250-7, (2001) (PubMed).

Kimura, Ito, Amano, Chihara, Fukata, Nakafuku, Yamamori, Feng, Nakano, Okawa, Iwamatsu, Kaibuchi: "Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)" in: Science (New York, N.Y.), Vol. 273, Issue 5272, pp. 245-8, (1996) (PubMed).

Chen, Chen, Alessi, Campbell, Shanahan, Cohen, Cohen: "Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M." in: FEBS letters, Vol. 356, Issue 1, pp. 51-5, (1995) (PubMed).

Aliases for PPP1R12A 抗体

protein phosphatase 1, regulatory (inhibitor) subunit 12A (Ppp1r12a) 抗体
protein phosphatase 1 regulatory subunit 12A (PPP1R12A) 抗体
protein phosphatase 1, regulatory subunit 12A (Ppp1r12a) 抗体
1200015F06Rik 抗体
5730577I22Rik 抗体
AA792106 抗体
AV099298 抗体
D10Ertd625e 抗体
M110 抗体
M130 抗体
MBS 抗体
MBSP 抗体
Mypt1 抗体
MYPT1 抗体

您还需要查找其他产品吗？

You are here:

PPP1R12A 抗体 by Grade

PPP1R12A 抗体 by 适用

PPP1R12A 抗体 by 应用范围

PPP1R12A 抗体 by 抗体来源

PPP1R12A 抗体 by 抗原表位

PPP1R12A 抗体 by 克隆形成能力

PPP1R12A 抗体 by 克隆

PPP1R12A 抗体 by 标记

Popular PPP1R12A 抗体

Latest Publications for our PPP1R12A 抗体

Aliases for PPP1R12A 抗体

您还需要查找其他产品吗？

antibodies-online

genomics-online