This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012].
Allen, Kwon, Nairn, Greengard: "Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit." in: The Journal of biological chemistry, Vol. 273, Issue 7, pp. 4089-95, (1998) (PubMed).