PPM1B 产品
(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008].
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Featured PPM1B Categories
PPM1B 抗体
High quality antibodies with extensive validation data.
PPM1B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PPM1B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPM1B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN5774361
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (2)
Cat. No.
ABIN519087
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7246856
Quantity
200 μL
Datasheet
Datasheet
Recommended PPM1B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958949
Quantity
96 tests
Datasheet
Datasheet
Recommended PPM1B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3133917
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3086363
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5710135
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PPM1B Products
: "Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cβ." in: The Journal of biological chemistry, Vol. 287, Issue 19, pp. 15193-204, (2012) (PubMed).: "The 2p21 deletion syndrome: characterization of the transcription content." in: Genomics, Vol. 86, Issue 2, pp. 195-211, (2005) (PubMed).
: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004) (PubMed).
: "Uniquely conserved non-translated regions are involved in generation of the two major transcripts of protein phosphatase 2Cbeta." in: Journal of molecular biology, Vol. 312, Issue 3, pp. 439-51, (2001) (PubMed).
Synonyms and alternative names related to PPM1B
protein phosphatase, Mg2+/Mn2+ dependent 1B (PPM1B), protein phosphatase 1B, magnesium dependent, beta isoform (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1B (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog (ppm1b.L), protein phosphatase, Mg2+/Mn2+ dependent 1B (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1Ba (ppm1ba), PP2C-beta-X, pp2c-beta-x, Pp2c2, PP2CB, pp2cb, PP2CBETA, pp2cbeta, PPC2BETAX, ppc2betax, zgc:92031Protein level used designations for PPM1B
- PP2C-beta
- protein phosphatase 1B
- protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform
- protein phosphatase 2C isoform beta
- protein phosphatase 2C-like protein
- Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform
- Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform
- protein phosphatase 1B, magnesium dependent, beta isoform
- protein phosphatase type 2C beta
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