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POM121 产品

(POM121 Membrane Glycoprotein (POM121))

Categories

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and multiple pseudogenes have been identified. [provided by RefSeq, Mar 2012].

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Featured POM121 Categories

POM121 抗体

High quality antibodies with extensive validation data.

Recommended POM121 抗体

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Reactivity Human
Application WB, IF, IHC (p), ICC
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Cat. No. ABIN2855297
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
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Cat. No. ABIN7246724
Quantity 200 μL
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Cat. No. ABIN6264352
Quantity 100 μL
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Recommended POM121 ELISA试剂盒

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Analytical Method
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6233749
Quantity 96 tests
Datasheet Datasheet

Recommended POM121 蛋白

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Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3117339
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Cat. No. ABIN3136592
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Latest Publications for our POM121 Products

Bilir, Kojidani, Mori, Osakada, Kobayashi, Koujin, Hiraoka, Haraguchi: "Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 24, Issue 5, pp. 338-353, (2019) (PubMed).

Ma, Li, Jia, Gong, Wang, Zhang, Gu, Tang: "POM121 is identified as a novel prognostic marker of oral squamous cell carcinoma." in: Journal of Cancer, Vol. 10, Issue 19, pp. 4473-4480, (2019) (PubMed).

Rodriguez-Bravo, Pippa, Song, Carceles-Cordon, Dominguez-Andres, Fujiwara, Woo, Koh, Ertel, Lokareddy, Cuesta-Dominguez, Kim, Rodriguez-Fernandez, Li, Gordon, Hirschfield, Prats, Reddy, Fatatis et al.: "Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import. ..." in: Cell, Vol. 174, Issue 5, pp. 1200-1215.e20, (2019) (PubMed).

Guo, Liu, Wu, Hu, Peng, Wu, Xiong, Dong: "The transmembrane nucleoporin Pom121 ensures efficient HIV-1 pre-integration complex nuclear import." in: Virology, Vol. 521, pp. 169-174, (2018) (PubMed).

Kim, Chung, Kim, Lee, Kim, Bae, Choi, Hewitt: "Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma." in: Frontiers in oncology, Vol. 8, pp. 465, (2018) (PubMed).

Jiang, Gan, Yen, Moussaud, McLean, Dickson: "Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons." in: Acta neuropathologica, Vol. 132, Issue 1, pp. 77-91, (2017) (PubMed).

Schwartz, Travesa, Martell, Forbes: "Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin." in: Nucleus (Austin, Tex.), Vol. 6, Issue 1, pp. 40-54, (2015) (PubMed).

Chow, Elgort, Dasso, Powers, Ullman: "The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function." in: Molecular biology of the cell, Vol. 25, Issue 1, pp. 160-8, (2014) (PubMed).

Synonyms and alternative names related to POM121

POM121 transmembrane nucleoporin (POM121), nuclear pore membrane protein 121 (Pom121), POM121 transmembrane nucleoporin (Pom121), POM121 transmembrane nucleoporin C-like (POM121CL), POM121 transmembrane nucleoporin C (POM121C), POM121 transmembrane nucleoporin (pom121), nuclear envelope pore membrane protein POM 121C (LOC100604279), POM121 membrane glycoprotein b (pom121-b), 2610027A18Rik, C80273, mKIAA0618, P145, POM121, POM121A, POM121C, wu:fa16c07, wu:fl35g12

Protein level used designations for POM121

  • POM121 membrane glycoprotein
  • nuclear envelope pore membrane protein POM 121
  • nuclear envelope pore membrane protein POM 121A
  • nuclear pore membrane protein 121 kDa
  • nucleoporin Nup121
  • pore membrane protein of 121 kDa
  • P145
  • nuclear pore membrane glycoprotein 121 kD
  • nuclear pore membrane protein 121
  • POM121 membrane glycoprotein C
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