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POLR3E 产品

(Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific periphjeric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

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Featured POLR3E Categories

POLR3E 抗体

High quality antibodies with extensive validation data.

POLR3E 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLR3E 抗体

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Reactivity
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Datasheet
Reactivity Human
Application ELISA, IHC, WB, IF
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  • (2)
Cat. No. ABIN7187807
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
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Cat. No. ABIN7150462
Quantity 100 μg
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Reactivity Human, Mouse
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Cat. No. ABIN3186524
Quantity 100 μL
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Recommended POLR3E 蛋白

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Quantity 10 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3095068
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Reactivity Mouse
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Cat. No. ABIN3137060
Quantity 1 mg
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Latest Publications for our POLR3E Products

Cristóbal-Mondragón, Lara-Chacón, Santiago, De-la-Rosa, González-González, Muñiz-Luna, Ladrón-de-Guevara, Romero-Romero, Rangel-Yescas, Fernández Velasco, Islas, Pastor, Sánchez-Olea, Calera: "FRET-based analysis and molecular modeling of the human GPN-loop GTPases 1 and 3 heterodimer unveils a dominant-negative protein complex." in: The FEBS journal, (2019) (PubMed).

Birch, Tan, Panov, Panova, Andersen, Owen-Hughes, Russell, Lee, Zomerdijk: "FACT facilitates chromatin transcription by RNA polymerases I and III." in: The EMBO journal, Vol. 28, Issue 7, pp. 854-65, (2009) (PubMed).

Hu, Wu, Sun, Yuan, Kobayashi, Myers, Hernandez: "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits." in: Molecular and cellular biology, Vol. 22, Issue 22, pp. 8044-55, (2002) (PubMed).

Synonyms and alternative names related to POLR3E

RNA polymerase III subunit E (POLR3E), polymerase (RNA) III (DNA directed) polypeptide E (Polr3e), polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog (polr3e.L), polymerase (RNA) III (DNA directed) polypeptide E (80kD) (polr3e), DNA-directed RNA polymerase III subunit RPC5 (LOC608689), RNA polymerase III subunit E (Polr3e), polymerase (RNA) III (DNA directed) polypeptide E (polr3e), MGC78924, RGD1308086, RPC5, SIN, Sin, wu:fb12d10, wu:fs42e03, zgc:55592

Protein level used designations for POLR3E

  • DNA-directed RNA polymerase III 80 kDa polypeptide
  • DNA-directed RNA polymerase III subunit RPC5
  • RNA polymerase III 80 kDa subunit RPC5
  • RNA polymerase III subunit C5
  • RNA polymerase III polypeptide E
  • RNA polymerase III subunit 5
  • sex-lethal interactor homolog
  • polymerase (RNA) III (DNA directed) polypeptide E (80kD)
  • polymerase (RNA) III (DNA directed) polypeptide E
  • polymerase (RNA) III subunit E
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