Purine Nucleoside Phosphorylase 抗体
(Purine Nucleoside Phosphorylase (PNP))
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008].
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Latest Publications for our Purine Nucleoside Phosphorylase 抗体
: "CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis." in: Journal of hepatology, Vol. 69, Issue 3, pp. 705-717, (2018) (PubMed).: "Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer." in: British journal of cancer, Vol. 106, Issue 2, pp. 405-13, (2012) (PubMed).
Aliases for Purine Nucleoside Phosphorylase 抗体
purine nucleoside phosphorylase (PNP) 抗体purine nucleoside phosphorylase (Pnp) 抗体
purine-nucleoside phosphorylase (Pnp) 抗体
AL024301 抗体
AU015798 抗体
NP 抗体
Np 抗体
Np-1 抗体
Np-2 抗体
Pnp1 抗体
PRO1837 抗体
PUNP 抗体
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