This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
Ménégaut, Masson, Abello, Denimal, Truntzer, Ducoroy, Lagrost, Pais de Barros, Athias, Petit, Martin, Steinmetz, Kretz: "Specific enrichment of 2-arachidonoyl-lysophosphatidylcholine in carotid atheroma plaque from type 2 diabetic patients." in: Atherosclerosis, Vol. 251, pp. 339-47, (2016) (PubMed).
Ali, Kokotos, Magrioti, Bone, Mobley, Hancock, Ramanadham: "Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes." in: PLoS ONE, Vol. 8, Issue 8, pp. e71748, (2013) (PubMed).
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Pattabiraman, Lih, Tomer, Rao: "The role of calcium-independent phospholipase A2γ in modulation of aqueous humor drainage and Ca2+ sensitization of trabecular meshwork contraction." in: American journal of physiology. Cell physiology, Vol. 302, Issue 7, pp. C979-91, (2012) (PubMed).