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PLK4 产品

(Polo-Like Kinase 4 (PLK4))

Categories

This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Featured PLK4 Categories

PLK4 抗体

High quality antibodies with extensive validation data.

PLK4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PLK4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, FACS
Validations
  • (3)
Cat. No. ABIN184701
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
Cat. No. ABIN524161
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243950
Quantity 200 μL
Datasheet Datasheet

Recommended PLK4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231852
Quantity 96 tests
Datasheet Datasheet

Recommended PLK4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569748
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315441
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094643
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PLK4 Products

Hori, Barnouin, Snijders, Toda: "A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation." in: EMBO reports, Vol. 17, Issue 3, pp. 326-37, (2016) (PubMed).

Hori, Peddie, Collinson, Toda: "Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly." in: Molecular biology of the cell, Vol. 26, Issue 11, pp. 2005-19, (2015) (PubMed).

Wang, Soni, Uryu, Tsou: "The conversion of centrioles to centrosomes: essential coupling of duplication with segregation." in: The Journal of cell biology, Vol. 193, Issue 4, pp. 727-39, (2011) (PubMed).

Rizki, Mott, Bissell: "Polo-like kinase 1 is involved in invasion through extracellular matrix." in: Cancer research, Vol. 67, Issue 23, pp. 11106-10, (2007) (PubMed).

Yamashita, Kajigaya, Yoshida, Ueno, Ota, Ohmine, Ueda, Miyazato, Ohya, Kitamura, Ozawa, Mano: "Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 39012-20, (2001) (PubMed).

Hudson, Chen, Fode, Binkert, Dennis: "Sak kinase gene structure and transcriptional regulation." in: Gene, Vol. 241, Issue 1, pp. 65-73, (2000) (PubMed).

Synonyms and alternative names related to PLK4

Sak kinase (SAK), polo like kinase 4 (PLK4), polo like kinase 4 (Plk4), polo-like kinase 4 (Plk4), polo-like kinase 4 (Drosophila) (plk4), serine/threonine-protein kinase PLK4 (LOC5571876), 1700028H20, AI385771, CG7186, Dmel\\CG7186, DmSAK, PLK-4, PLK4, Plk4, plk4, Sak, sak, SAK, SAK/PLK, SAK/PLK4, STK18, Stk18, stk18, wu:fi33g07

Protein level used designations for PLK4

  • CG7186-PA
  • SAK-PA
  • PLK-4
  • Snk akin kinase
  • serine/threonine kinase 18
  • serine/threonine protein kinase SAK
  • serine/threonine-protein kinase 18
  • serine/threonine-protein kinase PLK4
  • serine/threonine-protein kinase Sak
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