(Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5))
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
Ngok, Geyer, Kourtidis, Storz, Anastasiadis: "Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) Syx." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6640-50, (2013) (PubMed).
Ngok, Geyer, Liu, Kourtidis, Agrawal, Wu, Seerapu, Lewis-Tuffin, Moodie, Huveldt, Marx, Baraban, Storz, Horowitz, Anastasiadis: "VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx." in: The Journal of cell biology, Vol. 199, Issue 7, pp. 1103-15, (2012) (PubMed).
Aliases for PLEKHG5 抗体
pleckstrin homology and RhoGEF domain containing G5 (PLEKHG5) 抗体 pleckstrin homology domain containing, family G (with RhoGef domain) member 5a (plekhg5a) 抗体 pleckstrin homology and RhoGEF domain containing G5 (plekhg5) 抗体 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (Plekhg5) 抗体 pleckstrin homology and RhoGEF domain containing G5 (Plekhg5) 抗体 BC023181 抗体 DSMA4 抗体 GEF720 抗体 mKIAA0720 抗体 PLEKHG5 抗体 plekhg5 抗体 si:ch211-15p9.7 抗体 syx 抗体 Syx 抗体 syx-a 抗体 Tech 抗体