Plakophilin 2 抗体
(Plakophilin 2 (PKP2))
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008].
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Latest Publications for our Plakophilin 2 抗体
: "Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress." in: International journal of molecular sciences, Vol. 20, Issue 17, (2020) (PubMed).: "Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction." in: Nature communications, Vol. 8, pp. 13876, (2018) (PubMed).
: "Myocardial expression profiles of candidate molecules in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia compared to those with dilated cardiomyopathy and healthy controls." in: Heart rhythm, Vol. 13, Issue 3, pp. 731-41, (2016) (PubMed).
: "Plakophilin-1 localizes to the nucleus and interacts with single-stranded DNA." in: The Journal of investigative dermatology, Vol. 130, Issue 11, pp. 2638-46, (2010) (PubMed).
: "Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?" in: Cardiology, Vol. 115, Issue 2, pp. 148-54, (2010) (PubMed).
: "Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque." in: The Journal of cell biology, Vol. 135, Issue 4, pp. 1009-25, (1997) (PubMed).
Aliases for Plakophilin 2 抗体
plakophilin 2 (PKP2) 抗体plakophilin 2 (Pkp2) 抗体
1200008D14Rik 抗体
1200012P04Rik 抗体
AA516617 抗体
ARVD9 抗体
Pkp2l 抗体
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