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抗Human FOXO1 抗体:
抗Rat (Rattus) FOXO1 抗体:
抗Mouse (Murine) FOXO1 抗体:
Human Polyclonal FOXO1 Primary Antibody for ICC, IF - ABIN250693
Hoekstra, Sefton, Berry, Lu, Hardt, Marsh, Yin, Clardy, Chakravarti, Bulun, Kim: Progestins activate the AKT pathway in leiomyoma cells and promote survival. in The Journal of clinical endocrinology and metabolism 2009
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Human Polyclonal FOXO1 Primary Antibody for IHC - ABIN966149
Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. in The Biochemical journal 2004
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Human Polyclonal FOXO1 Primary Antibody for IF, IHC - ABIN362088
Zhan, Wang, Li, Xu, Sun, Xu: Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats. in Journal of neurochemistry 2010
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Human Polyclonal FOXO1 Primary Antibody for IHC (fro), IF - ABIN4948288
Sajan, Ivey, Lee, Mastorides, Jurczak, Samuels, Shulman, Braun, Leitges, Farese: PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes. in Molecular endocrinology (Baltimore, Md.) 2014
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Human Monoclonal FOXO1 Primary Antibody for ICC, IHC - ABIN969521
Lau, Koty, Nalbantoglu: Differential response of glioma cells to FOXO1-directed therapy. in Cancer research 2009
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Human Polyclonal FOXO1 Primary Antibody for IHC - ABIN966148
Gan, Zheng, Chabot, Unterman, Quirion: Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors. in Journal of neurochemistry 2005
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Human Polyclonal FOXO1 Primary Antibody for ICC, IF - ABIN4312363
Sahu, Laakso, Ovaska, Mirtti, Lundin, Rannikko, Sankila, Turunen, Lundin, Konsti, Vesterinen, Nordling, Kallioniemi, Hautaniemi, Jänne: Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. in The EMBO journal 2011
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Human Polyclonal FOXO1 Primary Antibody for IF, IHC - ABIN362738
Smith, Norton, Gorospe, Jiang, Nemoto, Holbrook, Finkel, Kusiak: Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. in The Journal of cell biology 2005
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Human Polyclonal FOXO1 Primary Antibody for ELISA, WB - ABIN252951
Paik, Kollipara, Chu, Ji, Xiao, Ding, Miao, Tothova, Horner, Carrasco, Jiang, Gilliland, Chin, Wong, Castrillon, DePinho: FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. in Cell 2007
AQP9 (显示 AQP7 抗体) overexpression decreased the protein levels of phosphatidylinositol-3-kinase (PI3K (显示 PIK3CA 抗体)), leading to reduced phosphorylation of Akt (显示 AKT1 抗体), and subsequently the protein levels of forkhead box protein O1 (FOXO1) were increased.
High glucose triggers IL-1beta (显示 IL1B 抗体) synthesis in retinal endothelial cells. The produced IL-1beta (显示 IL1B 抗体) induces increased FoxO1 expression, and interacts with the IL-1 (显示 IL1A 抗体) receptor to activate MAPK (显示 MAPK1 抗体) signaling, thereby inducing IL-1beta (显示 IL1B 抗体) autostimulation.
Results identified FOXO1 as a downstream effector of DKK3 that may play a role in blocking adrenocortical dedifferentiation.
Foxo1 signaling contributes to maintainance and exacerbation inflammation and insulin (显示 INS 抗体) resistance in polycystic ovary syndrome macrophages.
Low FOXO1 expression is associated with hepatocellular carcinoma.
presence of a new non-consensus FoxO1 binding site on the G6PC1 (显示 G6PC 抗体) promoter that overlaps the CRE, suggesting a mutual exclusion mechanism for FoxO1 and CREB (显示 CREB1 抗体) binding at the G6PC1 (显示 G6PC 抗体) promoter
miR (显示 MLXIP 抗体)-196a-5p specifically downregulates the expression of forkhead box protein O1 (FOXO1) by targeting its 3' untranslated region (3'-UTR (显示 UTS2R 抗体)). FOXO1 upregulates expression of phosphotyrosine interaction domain containing 1 (PID1 (显示 PID1 抗体)), thereby inhibiting GSC (显示 GSC 抗体) tumorigenicity and growth
we saw that GLP-1 (显示 GCG 抗体) induces phosphorylation of the epidermal growth factor receptor (显示 EGFR 抗体) and activation of Foxo1, resulting in cell growth with concomitant enzyme release. Our work uncovers GLP-1 (显示 GCG 抗体)-induced signaling pathways in the exocrine pancreas and suggests that increases in amylase (显示 AMY 抗体) and lipase (显示 LIPG 抗体) levels in subjects treated with GLP-1 receptor (显示 GLP1R 抗体) agonists reflect adaptive growth rather than early-stage pancreatitis.
These data suggest that high doses of insulin (显示 INS 抗体) downregulate apoA-I (显示 APOA1 抗体) gene expression in HepG2 cells through redistribution of FOXO1/LXRbeta (显示 NR1H2 抗体) complex, FOXA2 (显示 FOXA2 抗体), and LXRalpha (显示 NR1H3 抗体) on hepatic enhancer of apoA-I (显示 APOA1 抗体) gene.
FOXO1 inhibits the self-renewal capacity of gastric cancer cells through interaction with LGR5 (显示 LGR5 抗体).
These results indicate that miR (显示 MYLIP 抗体)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (显示 GAS6 抗体) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (显示 AKT1 抗体)-dependent inactivation of FOXO1a.
Trehalose may rescue against insulin (显示 INS 抗体) resistance-induced myocardial contractile defect and apoptosis, via autophagy associated with dephosphorylation of p38 MAPK (显示 MAPK14 抗体) and Foxo1 without affecting phosphorylation of Akt (显示 AKT1 抗体).
FoxO1 is a key mediator involved in glucose homeostasis and indicate that 1,25(OH)2D3 improves glucose metabolism and bone development
Data show that the mitochondrial enriched GCN5 (显示 KAT2A 抗体)-like 1 protein (GCN5L1 (显示 BLOC1S1 抗体)) controls hepatic glucose production by regulating FoxO1 protein levels.
Setdb1 (显示 SETDB1 抗体) regulates PTEN (显示 PTEN 抗体)/AKT (显示 AKT1 抗体)/FOXO1 pathway to inhibit Spermatogonial stem cells apoptosis.
These findings indicate that IGF-II reduces PGC-1alpha (显示 PPARGC1A 抗体) expression in skeletal muscle cells through a mechanism involving PI3K-Akt (显示 AKT1 抗体)-FoxO1 but not p38 MAPK (显示 MAPK14 抗体) or Erk1/2 (显示 MAPK1/3 抗体) MAPK (显示 MAPK1 抗体) pathways.
a critical role for FOXO (显示 FOXO3 抗体) transcription factors in mediating these proliferative versus apoptotic fates
L. donovani triggered AKT (显示 AKT1 抗体) activation to regulate GSK-3beta (显示 GSK3b 抗体)/beta-catenin (显示 CTNNB1 抗体)/FOXO-1 axis.
The data suggest autocrine nitric oxide/atrial natriuretic peptide (显示 NPPA 抗体)-induced activation of protein kinase (显示 CDK7 抗体) G type Ialpha/p-AKT (显示 AKT1 抗体)/p-FOXO1 promotes survival and proliferation in pancreatic beta-cells.
Myocardial ischemia is associated with downregulation and posttranslational modification of cardiac FoxO1. In a mouse model of postischemic heart failure, posttranslational modulation of FoxO1 alters heart function involving collagen and protein metabolism.
Cell fate and metabolic state are linked by transcriptional regulators, such as IRF4 (显示 IRF4 抗体) and FoxO1, with dual roles in lineage and metabolic choice. Instructing some cells to utilize nutrients for anabolism and differentiation while other cells catabolically self-digest and self-renew may enable growth and repair in metazoa.
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 抗体)-mTOR (显示 FRAP1 抗体)-FOXO1 signaling and suppressing the activation of TLR4 (显示 TLR4 抗体) and/or NOD2 (显示 NOD2 抗体) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (显示 MAP3K1 抗体) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (显示 MYLIP 抗体)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (显示 MYLIP 抗体)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (显示 MYH7 抗体) negatively and MyHC IIx and MyHC IIb (显示 MYH4 抗体) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (显示 TNFSF10 抗体) and Fas ligand FasL (显示 FASL 抗体) expression during follicular atresia.
Data show that IL-4 (显示 IL4 抗体) induces upregulation of the junction protein claudin-5 (显示 CLDN5 抗体) in endothelial cells (ECs) through activation of Jak (显示 JAK3 抗体)/STAT6 (显示 STAT6 抗体) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (显示 CEBPB 抗体) regulate preadipocyte adipogenesis possibly through C/EBPb (显示 CEBPB 抗体)-> FoxO1-> C/EBPb (显示 CEBPB 抗体) feedback regulatory loop and FoxO1-C/EBPb (显示 CEBPB 抗体) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (显示 PI3 抗体)-kinase and Akt (显示 AKT1 抗体) are activated after renal ischemia/reperfusion and that Akt (显示 AKT1 抗体) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (显示 FOXO3 抗体), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (显示 SIRT1 抗体) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (显示 FOXO3 抗体) is a key regulator of ROS (显示 ROS1 抗体)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (显示 NCAM1 抗体)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (显示 TNF 抗体) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (显示 SOD1 抗体) and catalase (显示 CAT 抗体) mRNA and protein levels in this organ.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like