PIK3C2A 抗体
(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008].
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38 results
Latest Publications for our PIK3C2A 抗体
: "Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function. ..." in: Cancer cell, Vol. 32, Issue 4, pp. 444-459.e7, (2017) (PubMed).: "miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. 291-6, (2014) (PubMed).
: "The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment." in: EMBO reports, Vol. 11, Issue 6, pp. 473-8, (2010) (PubMed).
: "Phosphoinositide 3-kinase C2alpha is activated upon smooth muscle cell migration and regulated by alpha(v)beta(3) integrin engagement." in: Biochemical and biophysical research communications, Vol. 297, Issue 2, pp. 261-6, (2002) (PubMed).
: "The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles." in: The Journal of biological chemistry, Vol. 275, Issue 16, pp. 11943-50, (2000) (PubMed).
: "Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain." in: The Journal of biological chemistry, Vol. 271, Issue 23, pp. 13892-9, (1996) (PubMed).
Aliases for PIK3C2A 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (PIK3C2A) 抗体phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (Pik3c2a) 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (pik3c2a) 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog (pik3c2a.S) 抗体
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (LOC100548137) 抗体
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (Pik3c2a) 抗体
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (pik3c2a) 抗体
CPK 抗体
cpk 抗体
Cpk-m 抗体
PI3-K-C2(ALPHA) 抗体
PI3-K-C2A 抗体
pi3-k-c2a 抗体
PI3KC2 抗体
sb:cb156 抗体
si:dkey-24l11.7 抗体
wu:fc02a04 抗体
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