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PIGP 产品

(Phosphatidylinositol Glycan Anchor Biosynthesis, Class P (PIGP))

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This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured PIGP Categories

PIGP 抗体

High quality antibodies with extensive validation data.

PIGP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIGP 抗体

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Reactivity
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Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC
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Cat. No. ABIN6264206
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
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Cat. No. ABIN7163218
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
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Cat. No. ABIN565565
Quantity 100 μg
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Recommended PIGP ELISA试剂盒

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Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6216337
Quantity 96 tests
Datasheet Datasheet

Recommended PIGP 蛋白

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Cat. No. ABIN1315031
Quantity 10 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3098767
Quantity 1 mg
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Reactivity Mouse
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Cat. No. ABIN3129973
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Latest Publications for our PIGP Products

Uhlén, Oksvold, Älgenäs, Hamsten, Fagerberg, Klevebring, Lundberg, Odeberg, Pontén, Kondo, Sivertsson: "Antibody-based protein profiling of the human chromosome 21." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. M111.013458, (2012) (PubMed).

Choi, Suzuki, Yoshimura, Togashi, Hida, Taylor, Wang, Sugano, Hattori, Sakaki: "Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5)." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 12, Issue 5, pp. 347-51, (2001) (PubMed).

Togashi, Choi, Taylor, Suzuki, Sugano, Hattori, Sakaki: "A novel gene, DSCR5, from the distal Down syndrome critical region on chromosome 21q22.2." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 3, pp. 207-12, (2000) (PubMed).

Watanabe, Murakami, Marmor, Inoue, Maeda, Hino, Kangawa, Julius, Kinoshita: "Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2." in: The EMBO journal, Vol. 19, Issue 16, pp. 4402-11, (2000) (PubMed).

Synonyms and alternative names related to PIGP

phosphatidylinositol glycan anchor biosynthesis class P (PIGP), phosphatidylinositol glycan anchor biosynthesis class P (pigp), phosphatidylinositol glycan anchor biosynthesis, class P (Pigp), phosphatidylinositol glycan anchor biosynthesis, class P (pigp), DCRC, dcrc, Dcrc, DCRC-S, dcrc-s, DSCR5, dscr5, Dscr5, DSRC, dsrc, PIGP, Pigp, wu:fc66d08, zgc:73366

Protein level used designations for PIGP

  • Down syndrome critical region gene 5
  • Down syndrome critical region protein 5
  • Down syndrome critical region protein C
  • PIG-P
  • phosphatidylinositol N-acetylglucosaminyltransferase subunit P
  • phosphatidylinositol glycan, class P
  • phosphatidylinositol-glycan biosynthesis class P protein
  • phosphatidylinositol-n-acetylglucosaminyltranferase subunit
  • Down syndrome critical region gene c
  • Down syndrome critical region homolog 5
  • down syndrome critical region protein 5 homolog
  • phosphatidylinositol glycan anchor biosynthesis, class P
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