PIGA 抗体
(Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010].
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Latest Publications for our PIGA 抗体
: "On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 12, pp. 3081-4, (2007) (PubMed).Aliases for PIGA 抗体
phosphatidylinositol glycan anchor biosynthesis class A (PIGA) 抗体phosphatidylinositol glycan anchor biosynthesis, class A (Piga) 抗体
phosphatidylinositol glycan anchor biosynthesis, class A (piga) 抗体
phosphatidylinositol glycan anchor biosynthesis class A (Piga) 抗体
AI194334 抗体
GPI3 抗体
im:6911675 抗体
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PIG-A 抗体
Pig-a 抗体
zgc:56589 抗体
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