PIAS2 抗体
(Protein Inhibitor of Activated STAT, 2 (PIAS2))
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011].
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Latest Publications for our PIAS2 抗体
: "BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 27, pp. 11294-9, (2009) (PubMed).: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).
: "FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 38035-46, (2005) (PubMed).
: "A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15505-14, (2004) (PubMed).
: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).
: "Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter." in: Oncogene, Vol. 22, Issue 3, pp. 351-60, (2003) (PubMed).
: "Inhibition of Stat1-mediated gene activation by PIAS1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 18, pp. 10626-31, (1998) (PubMed).
Aliases for PIAS2 抗体
protein inhibitor of activated STAT 2 L homeolog (pias2.L) 抗体protein inhibitor of activated STAT 2 (PIAS2) 抗体
protein inhibitor of activated STAT, 2 (pias2) 抗体
protein inhibitor of activated STAT 2 (Pias2) 抗体
protein inhibitor of activated STAT, 2 (Pias2) 抗体
6330408K17Rik 抗体
AI462206 抗体
ARIP3 抗体
AU018068 抗体
Dib 抗体
DIP 抗体
MGC83751 抗体
MIZ 抗体
Miz1 抗体
MIZ1 抗体
PIAS2 抗体
piasx 抗体
PIASX 抗体
PIASX-ALPHA 抗体
PIASX-BETA 抗体
PIASxalpha 抗体
PIASxb 抗体
PIASxbeta 抗体
SIZ2 抗体
wu:fi05f09 抗体
ZMIZ4 抗体
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