Phospholamban 抗体
(Phospholamban (PLN))
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].
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92 results
PLN
适用: 人
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
PLN
适用: 人
WB
宿主: 兔
Polyclonal
RB44799
unconjugated
1 image
4 references
PLN
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
PLN
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
PLN
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
Latest Publications for our Phospholamban 抗体
: "Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes." in: Cellular signalling, Vol. 63, pp. 109362, (2019) (PubMed).: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." in: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).
: "Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction." in: Molecular and cellular biology, Vol. 32, Issue 4, pp. 740-50, (2012) (PubMed).
: "The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy." in: European journal of heart failure, Vol. 11, Issue 11, pp. 1031-5, (2009) (PubMed).
: "Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes." in: American journal of physiology. Cell physiology, Vol. 296, Issue 5, pp. C992-C1002, (2009) (PubMed).
: "Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 32, Issue 2, pp. 333-9, (2007) (PubMed).
: "Phospholamban: a key determinant of cardiac function and dysfunction." in: Archives des maladies du coeur et des vaisseaux, Vol. 98, Issue 12, pp. 1239-43, (2006) (PubMed).
: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).
: "Autologous stem cell transplantation for myocardial repair." in: American journal of physiology. Heart and circulatory physiology, Vol. 287, Issue 2, pp. H501-11, (2004) (PubMed).
: "Mutation of the phospholamban promoter associated with hypertrophic cardiomyopathy." in: Biochemical and biophysical research communications, Vol. 304, Issue 1, pp. 1-4, (2003) (PubMed).
Aliases for Phospholamban 抗体
phospholamban (PLN) 抗体phospholamban (pln) 抗体
phospholamban (Pln) 抗体
cmd1p 抗体
CMD1P 抗体
CMH18 抗体
LOC100226261 抗体
plb 抗体
PLB 抗体
Plb 抗体
Plm 抗体
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