PGC 抗体
(Pepsinogen C (PGC))
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009].
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Latest Publications for our PGC 抗体
: "Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity." in: Nature communications, Vol. 9, Issue 1, pp. 2419, (2019) (PubMed).: "Troy is expressed in human stomach mucosa and a novel putative prognostic marker of intestinal type gastric cancer." in: Oncotarget, Vol. 8, Issue 31, pp. 50557-50569, (2017) (PubMed).
: "Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis." in: Cancer research, Vol. 65, Issue 14, pp. 6220-7, (2005) (PubMed).
Aliases for PGC 抗体
progastricsin (pepsinogen C) (PGC) 抗体progastricsin (PGC) 抗体
progastricsin (pepsinogen C) (Pgc) 抗体
progastricsin (Pgc) 抗体
2210410L06Rik 抗体
CPGC 抗体
gastricsin 抗体
Gastricsin 抗体
PEPC 抗体
Pg-1 抗体
PG1 抗体
PGC 抗体
PGII 抗体
PGNC 抗体
Upg-1 抗体
Upg1 抗体
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