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PFN1 产品

(Profilin 1 (PFN1))

Categories

This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012].

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Featured PFN1 Categories

PFN1 抗体

High quality antibodies with extensive validation data.

PFN1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PFN1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PFN1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (6)
Cat. No. ABIN2783306
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN6264161
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS
Validations
  • (3)
Cat. No. ABIN6242521
Quantity 200 μL
Datasheet Datasheet

Recommended PFN1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6975471
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958795
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969560
Quantity 96 tests
Datasheet Datasheet

Recommended PFN1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Birch
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN7506039
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124569
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314757
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PFN1 Products

Paszek, Żmudka, Plens, Legutko, Rajs, Zajdel: "Evaluation of profilin 1 as a biomarker in myocardial infarction." in: European review for medical and pharmacological sciences, Vol. 24, Issue 15, pp. 8112-8116, (2020) (PubMed).

Huo, Li, Qiao, Shang, Cao, Hong, Xiao: "Comparative proteomics analysis of microvesicles in human serum for the evaluation of osteoporosis." in: Electrophoresis, Vol. 40, Issue 14, pp. 1839-1847, (2019) (PubMed).

Yang, Chen, Liu, Zhao, Zhuang, Sun, Wei, Zhao, Chen, Shen: "Association Study of Common Variants in PFN1 With Hypertension in a Han Chinese Population: A Case-Control Study and A Follow-up Study." in: American journal of hypertension, Vol. 30, Issue 10, pp. 1024-1031, (2018) (PubMed).

Eroglu, Unal, Guclu, Kocyigit, Karaman, Saglam, Gezer, Tas, Zararsiz, Eyileten, Aydin, Oguz, Gungor, Yilmaz: "The association of profilin-1 levels with survival in chronic kidney disease." in: European journal of clinical investigation, Vol. 47, Issue 12, (2018) (PubMed).

Chatziharalambous, Lygirou, Latosinska, Stravodimos, Vlahou, Jankowski, Zoidakis: "Analytical Performance of ELISA Assays in Urine: One More Bottleneck towards Biomarker Validation and Clinical Implementation." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149471, (2016) (PubMed).

Witt, Büttner, Jannasch, Matschke, Waldow: "Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling." in: Journal of molecular and cellular cardiology, Vol. 74, pp. 127-38, (2014) (PubMed).

Fan, Potdar, Gong, Eswarappa, Donnola, Lathia, Hambardzumyan, Rich, Fox: "Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation." in: Nature cell biology, Vol. 16, Issue 5, pp. 445-56, (2014) (PubMed).

van Blitterswijk, Baker, Bieniek, Knopman, Josephs, Boeve, Caselli, Wszolek, Petersen, Graff-Radford, Boylan, Dickson, Rademakers: "Profilin-1 mutations are rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia." in: Amyotrophic lateral sclerosis & frontotemporal degeneration, Vol. 14, Issue 5-6, pp. 463-9, (2013) (PubMed).

Stoeckelhuber, Scherer, Janssen, Slotta-Huspenina, Loeffelbein, Rohleder, Nieberler, Hasler, Kesting: "The human submandibular gland: immunohistochemical analysis of SNAREs and cytoskeletal proteins." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 60, Issue 2, pp. 110-20, (2012) (PubMed).

Fan, Arif, Gong, Jia, Eswarappa, Willard, Horowitz, Graham, Penn, Fox: "Stimulus-dependent phosphorylation of profilin-1 in angiogenesis." in: Nature cell biology, Vol. 14, Issue 10, pp. 1046-56, (2012) (PubMed).

Synonyms and alternative names related to PFN1

profilin (PRO2), profilin 1 (PFN1), profilin 1 L homeolog (pfn1.L), profilin 1 (pfn1), profilin 1 (Pfn1), profilin 1 (PRF1), profilin homolog 1 (prf1), Profilin-1 (pfn-1), ALS18, F6F22.21, F6F22_21, GmPRO1, GmPRO2, MGC130883, Pfn, PFN1, PRO1, profilin, Profilin-1, profilin-1, Profilin1, PROFILIN 1, profilin 1, sb:cb813, wu:fa91a03, XProfilin1

Protein level used designations for PFN1

  • profilin-2
  • profilin 1
  • fa91a03
  • epididymis tissue protein Li 184a
  • profilin I
  • profilin-1
  • actin binding protein
  • CL2097_1
  • CL2097_1(520)
  • CL2097_1_ov
  • ZmPRO1
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