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Zinc Finger Protein 265 (Zranb2) Peptide

Zranb2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN986707
发货至: 中国
  • 抗原 See all ZNF265 (Zranb2) products
    ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))
    宿主
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-ZNF265 antibody (Catalog #: ARP37747_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    ZNF265 (Zranb2) (Zinc Finger Protein 265 (Zranb2))
    背景
    ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.

    Alias Symbols: ZIS, ZIS1, ZIS2, ZNF265

    Protein Interaction Partner: EP300,SFRS12,SFRS17A,SMN2,SNRNP70,SRSF2,U2AF1,YY1,ZRANB2,ARRB1,SNRNP70,TRA2B,U2AF1,USP39

    Protein Size: 330
    分子量
    37 kDa
    基因ID
    9406
    NCBI登录号
    NM_203350, NP_976225
    UniProt
    Q5VV34
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