Zinc Metalloproteinase, Ste24 (Zmpste24) Peptide
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Quick Overview for Zinc Metalloproteinase, Ste24 (Zmpste24) Peptide (ABIN986530)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ZMPSTE24 antibody (Catalog #: ARP46665_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
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背景
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ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Size: 475 -
分子量
- 55 kDa
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基因ID
- 10269
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NCBI登录号
- NM_005857, NP_005848
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UniProt
- O75844
抗原
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