Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
产品特性
This is a synthetic peptide designed for use in combination with anti-YWHAZ antibody (Catalog #: ARP48047_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
14-3-3 zeta (YWHAZ)
背景
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
Alias Symbols: KCIP-1, MGC111427, MGC126532, MGC138156, YWHAD, 14-3-3-zeta
Protein Interaction Partner: AANAT,AKT1,CBL,CDC25B,HCVgp1,IGF1R,MAPKAPK2,MAPT,RAF1,SSH1,SSH1,SSH2,SSH3,TSC2,UCP2,UCP3,YWHAZ,AKT1,EGFR,MAPKAPK2,YWHAZ,AANAT,ABL1,ADAM22,ADRA2A,ADRA2B,ADRA2C,AKAP13,AKT1,ARHGEF2,ATP5A1,ATXN1,BAD,BCAR1,BCR,BRAF,BSPRY,C22orf9,CBL,CDC25A,CDC25B,CDC25C,CDK16,CDK17,CENPJ,CFL1,CLIC4,CRTC2,CSF2RB,CSNK1A1,DFFA,EGFR,ENO1,EPB41L1,EPB41L3,FOXO1,FOXO3,FOXO4,GABBR1,GP1BA,GP1BB,GP5,HDAC4,HMGN1,HSPA1A,HSPA1B,IGF1R,IL9R,ING1,INPP5A,IRS1,IRS2,KCNK15,KCNK3,KCNK9,KIAA1377,KIF1C,KIF5B,KLC2,KLC4,KRT18,KSR1,LARP1,LIMK1,MAP3K2,MAP3K3,MAP3K5,MAPK8,MAPKAPK2,MAPT,MARK2,MARK3,MARK4,MDM4,MINK1,MLF1,MST1R,NFATC2,NFATC4,NR4A1,PAK4,PARD3,PARD6A,PARD6B,PDC,PFKFB2,PPP1CC,PRKCA,PRKCD,PRKCI,PRLR,PTPN13,RAF1,RALGPS2,REM1,RGS3,RIN1,RRAD,SIK1,SIK3,SLC8A2,STK25,STK38,TBXA2R,TH,TJP2,TLK2,TNFAIP3,TP53,TPD52L1,TPH1,TRA2B,TRIM21,TSC1,TSC2,TUBB,UBB,UCP2,UCP3,VIM,WEE1,XRCC6,YWHAE,YWHAZ,AANAT,AKT1,BAD,BCAR1,BRAF,C22orf9,CBL,CDC25A,CDC25B,CDK16,CSF2RB,DFFA,EDC3,EPB41L3,FOXO1,FOXO3,GP1BA,GP1BB,HDAC4,HDAC7,HMGN1,HNRNPL,HRR25,IL9R,INPP5A,KIAA1377,KIF5B,KLC1,KLC4,LARP1,LIMK1,LYST,MAP3K5,MAPT,MEPCE,Mlxipl,NADK,NCKAP1,NFATC4,NOLC1,PABPC4,PAK4,PRKCA,PRKCD,PRKCE,PRKCI,PRKCZ,PRKD1,RAF1,RAI14,RALGPS2,REM1,RGS3,RPL31,RRAD,SAMD4B,SF3B1,SYN2,TERT,TJP2,TNFAIP3,TP53,TPH1,TRA2B,TSC1,TSC2,UCP2,UCP3,USP8,Usp8,VIM,XRCC6,YWHAZ