Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) Peptide
VPS4A
适用: 人
宿主: 合成
BP, WB
Quick Overview for Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) Peptide (ABIN986093)
抗原
VPS4A
(Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-VPS4A antibody (Catalog #: ARP54916_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
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背景
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VPS4A is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast.The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ22197, SKD1, SKD2, VPS4, VPS4-1, SKD1A
Protein Interaction Partner: CHMP4A,CHMP1A,CHMP1B,CHMP2A,CHMP4A,CHMP4B,CHMP4C,RND2,VPS4A,VPS4B,C19orf62,CHMP1A
Protein Size: 437 -
分子量
- 49 kDa
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基因ID
- 27183
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NCBI登录号
- NM_013245, NP_037377
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UniProt
- Q9UN37
抗原
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