Lysine (K)-Specific Demethylase 6A (KDM6A) (Middle Region) Peptide
KDM6A
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN986013
发货至:
中国
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Contact Info
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中国
北京 101111
北京 101111
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Quick Overview for Lysine (K)-Specific Demethylase 6A (KDM6A) (Middle Region) Peptide (ABIN986013)
抗原
KDM6A
(Lysine (K)-Specific Demethylase 6A (KDM6A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-UTX antibody (Catalog #: ARP39483_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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背景
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UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Alias Symbols: DKFZp686A03225, MGC141941, bA386N14.2, UTX, KABUK2
Protein Interaction Partner: SMAD9,TLE1,ASH2L,C13orf23,HIST3H3,MLL2,MLL3,N4BP2,NCOA6,PAXIP1,PPP6R3,RBBP5,TLE1,WDR5,ZNF281
Protein Size: 1401 -
分子量
- 154 kDa
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基因ID
- 7403
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NCBI登录号
- NM_021140, NP_066963
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UniProt
- O15550
抗原
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