Ubiquitin-Conjugating Enzyme E2C (UBE2C) Peptide
UBE2C
适用: 人
宿主: 合成
BP, WB
Quick Overview for Ubiquitin-Conjugating Enzyme E2C (UBE2C) Peptide (ABIN985806)
抗原
UBE2C
(Ubiquitin-Conjugating Enzyme E2C (UBE2C))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-UBE2C antibody (Catalog #: ARP43090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11,ANAPC2,ENO2,UBE2C,ANAPC2,BUB1B,CDC20,ENO2,MAD2L1,POLM,RNF216,UBASH3B
Protein Size: 179 -
分子量
- 20 kDa
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基因ID
- 11065
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NCBI登录号
- NM_007019, NP_008950
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UniProt
- O00762
抗原
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