U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Peptide
U2AF59
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN985792
发货至:
中国
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Contact Info
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中国
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Quick Overview for U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Peptide (ABIN985792)
抗原
U2AF2 (U2AF59)
(U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-U2AF2 antibody (Catalog #: ARP40284_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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背景
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U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Alias Symbols: U2AF65
Protein Interaction Partner: BAT1,SF1,SF3B1,U2AF1,ATXN1,BEND7,C1orf190,CHIC2,CPSF7,DDX6,DPPA2,DVL2,EPB41,KIAA0907,MAP1B,PRPF40A,PUF60,SF1,SIP1,SMAD5,SRPK1,SRPK2,SRSF1,SRSF11,SRSF2IP,TCERG1,THAP1,U2AF1,WT1,ZRSR2,BEND7,C1orf190,CHIC2,DPPA2,DVL2,KIAA0907,PUF60,RNPS1,SF1,SF3A2,SRPK2,SRSF1,SRSF11,SRSF2IP,TCERG1,THAP1,U2AF1,WT1
Protein Size: 471 -
分子量
- 52 kDa
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基因ID
- 11338
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NCBI登录号
- NM_001012478, NP_001012496
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UniProt
- Q96HC5
抗原
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