Tyrosine Kinase 2 (TYK2) (C-Term) Peptide
TYK2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN985784
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Tyrosine Kinase 2 (TYK2) (C-Term) Peptide (ABIN985784)
抗原
TYK2
(Tyrosine Kinase 2 (TYK2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- HRDLAARNVL LDNDRLVKIG DFGLAKAVPE GHEYYRVRED GDSPVFWYAP
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TYK2 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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背景
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This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Alias Symbols: JTK1
Protein Interaction Partner: GNB2L1,IFNAR2,IL12RB1,JAKMIP1,CBL,CRKL,EIF2AK2,FYN,GHR,GNB2L1,IFNAR2,IL13RA1,IL6ST,IRS1,IRS2,JAK1,JAKMIP1,LYN,PDGFRB,PIK3R1,PLAUR,PRMT5,PTAFR,PTPN1,PTPN6,PTPRC,STAM2,STAT1,STAT2,TYK2,VAV1,XRCC5,CBL,CRKL,ELP2,FYN,GHR,GNB2L1,IFNAR1,IL13RA1,IL6ST,IRS2,JAK1,L
Protein Size: 1187 -
分子量
- 134 kDa
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基因ID
- 7297
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NCBI登录号
- NM_003331, NP_003322
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UniProt
- P29597
抗原
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