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Tripartite Motif Containing 24 (TRIM24) (Middle Region) Peptide

TRIM24 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN985500
发货至: 中国
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Quick Overview for Tripartite Motif Containing 24 (TRIM24) (Middle Region) Peptide (ABIN985500)

抗原

TRIM24 (Tripartite Motif Containing 24 (TRIM24))

宿主

资源

  • 4
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    产品特性

    This is a synthetic peptide designed for use in combination with anti-TRIM24 antibody (Catalog #: ARP34449_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    TRIM24 (Tripartite Motif Containing 24 (TRIM24))

    背景

    The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1

    Protein Interaction Partner: ESR1,AR,CBX1,CBX3,CBX5,ESR1,ESR2,GTF2E1,HNF4A,HSPA1A,NR2F2,NR3C1,NR3C2,PGR,PML,RARA,RXRA,SUMO1,TAF11,TAF1B,TAF1C,TAF7,THRA,TRIM24,TRIM28,TRIM33,VDR,ZNF10,AR,ESR1,GTF2E1,NR3C1,NR3C2,PML,RARA,RXRA,TAF11,TAF7,THRA,TRIM24,TRIM28,TRIM33,ZNF10

    Protein Size: 1050

    分子量

    117 kDa

    基因ID

    8805

    NCBI登录号

    NM_015905, NP_056989

    UniProt

    O15164
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