Tripartite Motif Containing 23 (TRIM23) (N-Term) Peptide
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Quick Overview for Tripartite Motif Containing 23 (TRIM23) (N-Term) Peptide (ABIN985497)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TRIM23 antibody (Catalog #: ARP31998_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM23 (Tripartite Motif Containing 23 (TRIM23))
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背景
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TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Alias Symbols: ARD1, ARFD1, RNF46
Protein Interaction Partner: C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM29,TRIM31,ZNF250,ZNF581,C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM28,TRIM29,TRIM31,TRIM32,TRIM6,ZNF250,ZNF581
Protein Size: 574 -
分子量
- 64 kDa
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基因ID
- 373
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NCBI登录号
- NM_001656, NP_001647
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UniProt
- P36406
抗原
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