Tribbles Pseudokinase 2 (TRIB2) (Middle Region) Peptide
TRIB2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN985471
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Tribbles Pseudokinase 2 (TRIB2) (Middle Region) Peptide (ABIN985471)
抗原
TRIB2
(Tribbles Pseudokinase 2 (TRIB2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TRIB2 antibody (Catalog #: ARP55377_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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背景
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TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
Alias Symbols: GS3955, TRB2, C5FW
Protein Interaction Partner: UBQLN4
Protein Size: 343 -
分子量
- 39 kDa
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基因ID
- 28951
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NCBI登录号
- NM_021643, NP_067675
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UniProt
- Q92519
抗原
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