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TNF Receptor-Associated Factor 1 (TRAF1) (Middle Region) Peptide

TRAF1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN985436
发货至: 中国
  • 抗原 See all TRAF1 products
    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TRAF1 antibody (Catalog #: AVARP09008_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
    背景
    This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: EBI6, MGC:10353

    Protein Interaction Partner: BIRC2,BIRC3,MAP3K14,TNFRSF8,TRAF2,BIRC2,BIRC3,CASP10,CASP3,CASP6,CASP8,CD40,CFLAR,EDAR,GFI1B,HIVEP3,MAP3K14,MAP6,NGFRAP1,RIPK1,RIPK2,SPOP,SRC,TANK,TICAM1,TNFAIP3,TNFRSF11A,TNFRSF12A,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF9,TRADD,TRAF2,TRAF3IP2,TRAIP,TRIM37,USP7,BIRC2,BIRC3,CASP10,CASP6,CASP8,CD27,CFLAR,HIVEP3,LTBR,MAP3K14,MAP3K5,NGFR,RIPK1,RIPK2,SPOP,SRC,TANK,TNFAIP3,TNFRSF11A,TNFRSF12A,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF9,TNFSF9,TRADD,TRAF2,TRAIP,TRIM37,USP7

    Protein Size: 416
    分子量
    46 kDa
    基因ID
    7185
    NCBI登录号
    NM_005658, NP_005649
    UniProt
    Q13077
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