Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) (Middle Region) Peptide
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Quick Overview for Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) (Middle Region) Peptide (ABIN985332)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TNKS1BP1 antibody (Catalog #: ARP58347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
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背景
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TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
Alias Symbols: FLJ45975, KIAA1741, TAB182
Protein Interaction Partner: TNKS,TNKS2,TNKS,TNKS2
Protein Size: 1729 -
分子量
- 190 kDa
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基因ID
- 85456
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NCBI登录号
- NM_033396, NP_203754
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UniProt
- Q9C0C2
抗原
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