Tyrosine Kinase, Non-Receptor, 1 (TNK1) (C-Term) Peptide
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Quick Overview for Tyrosine Kinase, Non-Receptor, 1 (TNK1) (C-Term) Peptide (ABIN985328)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- EIRQARAVPQ GPPGLPPRPP LSSSSPQPSQ PSRERLPWPK RKPPHNHPMG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TNK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
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背景
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The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC46193
Protein Interaction Partner: PLCG1,PLCG1,SFN,TNK1,UBC
Protein Size: 661 -
分子量
- 72 kDa
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基因ID
- 8711
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NCBI登录号
- NM_003985, NP_003976
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UniProt
- Q13470
抗原
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