Transmembrane Protease, serine 6 (TMPRSS6) (N-Term) Peptide
TMPRSS6
适用: 人
宿主: 合成
BP, IHC, WB
产品编号 ABIN985287
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for Transmembrane Protease, serine 6 (TMPRSS6) (N-Term) Peptide (ABIN985287)
抗原
TMPRSS6
(Transmembrane Protease, serine 6 (TMPRSS6))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TMPRSS6 antibody (Catalog #: ARP53188_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
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背景
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TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
Alias Symbols: IRIDA
Protein Interaction Partner: COL1A1,FN1,LAMA1
Protein Size: 811 -
分子量
- 90 kDa
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基因ID
- 164656
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NCBI登录号
- NM_153609, NP_705837
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UniProt
- Q8IU80
抗原
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