Transmembrane Protease, serine 6 (TMPRSS6) (N-Term) Peptide
TMPRSS6
适用: 人
宿主: 合成
BP, IHC, WB
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- 抗原 See all TMPRSS6 products
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TMPRSS6 antibody (Catalog #: ARP53188_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
- 别名
- IRIDA Peptide, 1300008A22Rik Peptide, transmembrane protease, serine 6 Peptide, transmembrane serine protease 6 Peptide, Tmprss6 Peptide, TMPRSS6 Peptide
- 背景
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TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
Alias Symbols: IRIDA
Protein Interaction Partner: COL1A1,FN1,LAMA1
Protein Size: 811 - 分子量
- 90 kDa
- 基因ID
- 164656
- NCBI登录号
- NM_153609, NP_705837
- UniProt
- Q8IU80
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