Toll-Like Receptor 8 (TLR8) (C-Term) Peptide
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Quick Overview for Toll-Like Receptor 8 (TLR8) (C-Term) Peptide (ABIN985141)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- LEPVLQHSQY LRLRQRICKS SILQWPDNPK AEGLFWQTLR NVVLTENDSR
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TLR8 Antibody(ARP59048_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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背景
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Alias Symbols: CD288, MGC119599, MGC119600
Protein Interaction Partner: BTK,MYD88
Protein Size: 1041 -
分子量
- 120 kDa
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基因ID
- 51311
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NCBI登录号
- NM_138636, NP_619542
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UniProt
- Q9NR97
抗原
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