Timeless Homolog (TIMELESS) Peptide
Our Local Distributor
北京 101111
Quick Overview for Timeless Homolog (TIMELESS) Peptide (ABIN985092)
抗原
宿主
资源
应用范围
-
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-TIMELESS antibody (Catalog #: ARP38403_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- TIMELESS (Timeless Homolog (TIMELESS))
-
背景
-
The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Alias Symbols: TIM, TIM1, hTIM
Protein Interaction Partner: CRY1,PER1,PER2,TIPIN,ATRIP,CHEK1,CLSPN,CRY2,Clock,PCNA,Per1,Per2,TIPIN,per
Protein Size: 1208 -
分子量
- 139 kDa
-
基因ID
- 8914
-
NCBI登录号
- NM_003920, NP_003911
-
UniProt
- Q9UNS1
抗原
-