TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) Peptide
TIA1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN985083
发货至:
中国
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Contact Info
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Quick Overview for TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) Peptide (ABIN985083)
抗原
TIA1
(TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TIA1 antibody (Catalog #: ARP40981_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) peptide
TIA1 适用: 人, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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背景
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TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Alias Symbols: TIA-1
Protein Interaction Partner: FASTK,FASTK
Protein Size: 375 -
分子量
- 42 kDa
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基因ID
- 7072
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NCBI登录号
- NM_022037, NP_071320
抗原
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