Thyroid Hormone Receptor, beta (THRB) (N-Term) Peptide
THRB
适用: 人
宿主: 合成
BP, WB, ChIP
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- 抗原 See all THRB products
- THRB (Thyroid Hormone Receptor, beta (THRB))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-THRB antibody (Catalog #: ARP37994_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Thyroid Hormone Receptor, beta (THRB) peptide
THRB 适用: 斑马鱼 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- THRB (Thyroid Hormone Receptor, beta (THRB))
- 别名
- C-ERBA-2 Peptide, C-ERBA-BETA Peptide, ERBA2 Peptide, GRTH Peptide, NR1A2 Peptide, PRTH Peptide, THR1 Peptide, THRB1 Peptide, THRB2 Peptide, Nr1a2 Peptide, T3R[b] Peptide, T3Rbeta Peptide, Thrb1 Peptide, Thrb2 Peptide, c-erbAbeta Peptide, TR-beta Peptide, TR[b]1 Peptide, fj24f03 Peptide, trb Peptide, wu:fj24f03 Peptide, CTR BETA 2 Peptide, TR-BETA Peptide, LOC734147 Peptide, thrb Peptide, THRB Peptide, C-erba-beta Peptide, RATT3REC Peptide, T3rec Peptide, TRbeta Peptide, THR Peptide, TRbeta1 Peptide, thyroid hormone receptor beta Peptide, thyroid hormone receptor, beta Peptide, thyroid hormone receptor, beta S homeolog Peptide, thyroid hormone receptor, beta L homeolog Peptide, THRB Peptide, Thrb Peptide, thrb Peptide, thrb.S Peptide, thrb.L Peptide
- 背景
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THRB is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several transcript variants have been observed for this gene, but the full-length nature of only one has been determined so far. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Alias Symbols: ERBA-BETA, ERBA2, GRTH, MGC126109, MGC126110, NR1A2, THR1, THRB1, THRB2, PRTH, C-ERBA-2, C-ERBA-BETA
Protein Interaction Partner: ANP32A,BTG1,CTCF,MED21,MPG,NCOA1,NCOA2,NCOA3,NCOA3,PRMT2,RXRB,ACVR1,BRD8,BTG1,C1D,CAMK2B,CCND1,CNOT1,COPS2,CTCF,ESR1,FOXO1,HDAC2,HMGN3,JMJD1C,MECR,MED1,MED21,MPG,NCOA1,NCOA2,NCOA3,NCOA6,NCOR1,NCOR2,NR2F6,NRBF2,NRIP1,PPARGC1A,PRMT2,PSMC3IP,PSMC5,RXRA,RXRB,RXRG,THRB,TP53,TRIP10,TRIP12,TRIP13,TRIP4,TRIP6,ZNHIT3,BRD8,CCND1,COPS2,EIF3I,Hdac2,NCOA1,NCOA2,NCOA6,NCOR2,NR2F6,NRBF2,PPARGC1A,PPARGC1B,PRMT1,PSMC5,RXRA,SRC,TBL1X,THRB,TP53,TRIP4,TSG101
Protein Size: 461 - 分子量
- 53 kDa
- 基因ID
- 7068
- NCBI登录号
- NM_000461, NP_000452
- UniProt
- P10828
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